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J Clin Pathol 57:73-76 doi:10.1136/jcp.57.1.73
  • Original article

Factors affecting metastases to non-sentinel lymph nodes in breast cancer

Table 3

Clinicopathological features associated with non-SLN metastases

Feature No. SLN+ No. (%) non-SLN+ Univariate analysis (p value) Multivariate analysis (p value)
T1b 4 1 (25%) 0.5972
T1c 12 5 (42%) 0.610
T2 33 18 (55%) 0.2382
T3 5 2 (40%) 0.1860
Metastasis size
    Micrometastasis 16 3 (19%)
    Macrometastasis 38 23 (61%) 0.005 0.024
Lymphovascular invasion
    Present 37 18 (49%) 0.913
    Absent 17 8 (47%)
Extranodal extension
    Present 11 10 (91%) 0.0015 0.0163
    Absent 43 16 (37%)
Patient age (years)
    <50 18 7 (39%) 0.3356
    >50 36 19 (53%)
Primary tumour location
    Upper outer quadrant 18 10 (55%) 0.5920
    Upper inner quadrant 9 4 (44%)
    Lover inner quadrant 4 3 (75%)
    Lower outer quadrant 7 2 (29%)
    Central 16 7 (44%)
Histological type
    Invasive ductal 39 17 (44%) 0.1342
    Invasive lobular 9 7 (77%)
    Mixed 6 2 (33%)
Grade
    I 6 2 (33%) 0.4411
    II 30 15 (50%) 0.7607
    III 18 9 (50%) 0.8473

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