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J Clin Pathol 57:58-63 doi:10.1136/jcp.57.1.58
  • Original article

Analysis of cell cycle regulator proteins in non-small cell lung cancer

Table 6

Multivariate Cox regression analysis of overall survival in patients with non-small cell lung cancer

RR of death 95% CI p Value
CI, confidence interval; NS, not significant; RR, relative risk.
Clinical staging
    Stage I–II 1
    Stage III (A/B) 3.450 1.43 to 6.78 0.001
Pathological N factor
    N0 1 0.089 (NS)
    N1–3 2.015 0.659 to 6.156
p53
    p53 negative 1 0.053 (NS)
    p53 positive 1.771 0.796 to 2.007
p21
    p21 positive 1 0.060 (NS)
    p21 negative 1.818 0.912 to 3.407
p16
    p16 positive 1 0.006 (NS)
    p16 negative 3.149 1.384 to 7.164

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