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J Clin Pathol 56:583-586 doi:10.1136/jcp.56.8.583
  • Original article

Enhanced telomere shortening in transformed lymphoblasts from patients with X linked dyskeratosis

Table 1

Cell death and proliferation in the cell lines studied over a period of 4 weeks

Percentage of dead cells (mean (SD))
Cell lines 1st week 2nd week 3rd week 4th week
GM00130c 16 (5) 18 (7) 19 (4) 25 (3)
GM00130c+IQ 16 (4) 17 (9) 30 (3)
GM03193 19 (4) 35 (7) 45 (11) 69 (8)
GM03194 17 (3) 14 (4) 70 (4) 89 (11)
GM03194+IQ 17 (1) 23 (7) 62 (13)
Cytofluorimetric hypodiploid peak (%)
Cell lines 1st week 2nd week 3rd week 4th week
IQ, 1,5-dihydroxyquinoline.
GM00130c 5.6 4.9 4.2 5.3
GM00130c+IQ 6.9 5.2 5.6
GM03193 8.2 16.8 20.2 48.7
GM03194 12.7 17.9 47.6 95.6
GM03194+IQ 17.0 22.8 78.0

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