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J Clin Pathol 56:575-578 doi:10.1136/jcp.56.8.575
  • Original article

Increase of bone marrow lymphocytes in systemic mastocytosis: reactive lymphocytosis or malignant lymphoma? Immunohistochemical and molecular findings on routinely processed bone marrow biopsy specimens

Table 1

Diagnosis, presence of lymphocytic clusters (LC), monoclonality of IgH/TCRγ, and point mutation Asp816-Val of c-kit

Case Diagnosis LC IgH TCRγ c-kit
SM, systemic mastocytosis.
1 Indolent SM + +
2 Indolent SM + +
3 Indolent SM + +
4 Indolent SM +
5 Indolent SM + +
6 Indolent SM +
7 Indolent SM +
8 Indolent SM + +
9 Indolent SM + +
10 Indolent SM + +
11 Indolent SM + +
12 Aggressive SM +
13 Aggressive SM +
15 Immunocytoma + +
16 Immunocytoma + +
17 Immunocytoma + +

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