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J Clin Pathol 56:283-286 doi:10.1136/jcp.56.4.283
  • Original article

How morphometric analysis of metastatic load predicts the (un)usefulness of PET scanning: the case of lymph node staging in melanoma

Table 1

Tumour volumetry of regional lymph nodes in 59 patients with cutaneous melanoma in relation to Breslow thickness and sentinel node status

Breslow thickness (mm) Patients with positive SN(s) Patients with positive non-SN(s)* Median total tumour volume in regional node* basin (mm3) (range)
*Assuming that the 2 patients refusing lymph node dissection (with uneventful follow up) had no involved nodes;
†95% confidence interval, 15% to 24%;
‡95% confidence interval, 12% to 34%.
0.76–1.5 19/122 (16%) 4/19 (21%) 0.01 (0.0001–118.86)
1.5–4.0 27/118 (23%) 5/27 (19%) 0.29 (0.0006–70.44)
⩾4.0 13/22 (59%) 4/13 (31%) 1.57 (0.004–55.06)
Total 59/308 (19%†) 13/59 (22%‡) 0.15 (0.0001–118.86)

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