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J Clin Pathol 56:205-208 doi:10.1136/jcp.56.3.205
  • Original article

Histological changes in the oesophageal squamous mucosa: correlation with ambulatory 24 hour pH monitoring

Table 3

Relation between severity of neutrophil inflammation in squamous mucosa and lower oesophageal sphincter/oesophageal body characteristics

Neutrophil inflammation
None (n=28) Mild (n=12) Moderate (n=11) Severe (n=11)
The contraction amplitude refers to the oesophageal contraction amplitudes 6, 11, and 16 cm below the upper oesophageal sphincter. *p<0.01 severe v none; †p<0.05 mild v none and v moderate; ‡p<0.01 severe v none and v moderate; §p<0.01 severe v none and p<0.05 severe v moderate; ¶p<0.01 severe v all other groups.
LOS, lower oesophageal sphincter.
LOS pressure (mm Hg) 11 (7–18) 10 (5–18) 10 (4–25) 5 (1–10)*
Contraction amplitude 6 cm 34 (22–55) 21 (20–31)† 49 (24–71) 18 (12–28)‡
Contraction amplitude 11 cm 64 (37–82) 52 (33–75) 60 (36–86) 31 (21–53)§
Contraction amplitude 16 cm 65 (45–91) 80 (43–120) 90 (43–118) 32 (18–43)¶

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