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J Clin Pathol 56:200-204 doi:10.1136/jcp.56.3.200
  • Original article

Expression of Ki-67 and cytokeratin 20 in hyperplastic polyps of the colorectum

Table 1

Comparison of Ki-67 and cytokeratin 20 (CK20) staining in atypical and typical hyperplastic polyps

Staining pattern Typical on light microspopy (n=26) Atypical on light microspopy (n=31)
Usual pattern (Ki-67 positivity confined to lower crypt, CK positivity confined to upper crypt) 17 11
Upper crypt zone Ki-67 positivity, usual pattern CK20 positivity 1 2
Usual pattern Ki-67 positivity with basal CK20 positivity 7 14
Upper crypt zone Ki-67 positivity and basal CK20 positivity 1 4
p=0.036 for CK20 differences (Fisher's exact test; p value for the same or stronger association); p=0.19 for Ki-67 differences (Fisher's exact test; p value for the same or stronger association).

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