Table 4
Monitor and reference INR for 535 target samples at 10 centres
| POCT system | Species specific IRP | Mean reference INR | Lyophilised plasma calibration | Mean monitor INR | Mean % difference | CI for mean % difference | p Value (paired t test) |
|---|---|---|---|---|---|---|---|
| Geometric means of reference and monitor INR values, percentage difference in geometric mean INR, corresponding 95% confidence intervals (CI), and p value are given. | |||||||
| INR, international normalised ratio; IRP, international reference preparation; POCT, point of care testing; RBT/90, rabbit plain international reference preparation; rTF/95, human recombinant international reference preparation. | |||||||
| CoaguChek Mini | RBT/90 | 2.50 | Artificially depleted | 2.77 | 10.8 | 8.9 to 12.7 | <0.0001 |
| Individual coumarin | 2.56 | 2.2 | 0.5 to 3.9 | 0.0099 | |||
| Pooled coumarin | 2.63 | 5.0 | 3.3 to 6.8 | <0.0001 | |||
| TAS PT-NC | rTF/95 | 2.46 | Artificially depleted | 2.16 | −12.0 | −13.2 to −10.8 | <0.0001 |
| Individual coumarin | 2.13 | −13.4 | −14.5 to −12.2 | <0.0001 | |||
| Pooled coumarin | 2.14 | −12.9 | −14.1 to −11.7 | <0.0001 | |||
