Multiple microcarcinoids in a patient with long standing ulcerative colitis
- 1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan
- 2Clinical and Surgical Oncology, Graduate School of Medical Sciences, Kyushu University
- 3Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University
- Correspondence to: Dr T Matsumoto Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan; mataneintmed2.med.kyushu-u.ac.jp
- Accepted 11 June 2003
Abstract
A male patient with a 17 year history of intractable ulcerative colitis of the entire type was treated by total proctocolectomy. Colonoscopy before surgery did not identify dysplasia. Histological examination of the resected colorectum revealed that, in addition to chronic inflammatory infiltrates, there were 21 areas of microcarcinoids located in the muscularis propria and in the superficial layer of the submucosa. Carcinoids may be more common than previously thought, and they may be a reactive phenomenon to a variety of factors in ulcerative colitis.
