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J Clin Pathol 56:956-959 doi:10.1136/jcp.56.12.956
  • Short report

Mannan binding lectin in febrile adults: no correlation with microbial infection and complement activation

Table 2

Circulating mannan binding lectin (MBL) and C3a in febrile medical patients, according to microbial infection

Group 1 (n = 115) Group 2 (n = 43) Group 3 (n = 19)
Values are median (range) or number (percentage), where appropriate.
Group 1, culture negative; group 2, local culture positive; group 3, bacteraemia (n = 7) or bacteraemia and positive local cultures (n = 12).
*p<0.05 (Kruskal-Wallis test); †p<0.05 (χ2 test).
MBL (μg/ml) 1.1 (0−12.3) 1.7 (0−10.0) 2.5 (0−6.4)
MBL <0.1 μg/ml 21 (18%) 9 (21%) 2 (11%)
MBL >1.5 μg/ml 53 (46%) 23 (53%) 12 (63%)
C3a (nmol/l) 7.4 (2.3−35.0)* 8.3 (2.4−21.0)* 8.1 (6.3−52.0)*
C3a >5 nmol/l 86 (75%)† 37 (86%)† 19 (100%)†

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