Chromosome 4 hyperploidy occurs early in premalignant Barrett’s oesophagus
Genetic aberrations are widespread in Barrett’s oesophagus, with aneuploidy developing well before dysplasia can be identified.
Endoscopic cytology brushings from patients with oesophageal dysplasia, Barrett’s metaplasia, and adenocarcinoma were cytospun to generate a single layer of interphase cells. The slides were prepared for …









