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J Clin Pathol 56:786-788 doi:10.1136/jcp.56.10.786
  • Short report

Detection of tumour lymphovascular space invasion using dual cytokeratin and CD31 immunohistochemistry

Table 1

The frequency of lymphovascular space invasion identified by conventional H&E staining compared with dual immunostaining for CK and CD31

CD31 and CK staining
H&E staining Present Absent Total
CK, pancytokeratin; H&E, haematoxylin and eosin.
Present 15 (14%) 2 (1.8%) 17 (16%)
“Probable” 2 (2%) 2 (2%) 4 (4%)
Absent 41 (38%) 46 (43%) 87 (80%)
Total 58 (54%) 50 (46%) 108

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