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J Clin Pathol 56:747-752 doi:10.1136/jcp.56.10.747
  • Original article

Prognostic significance of CD44 expression in diffuse large B cell lymphoma of activated and germinal centre B cell-like types: a tissue microarray analysis of 90 cases

Table 3

Tissue microarray analysis of the expression of CD44 standard isoform (CD44s) and its variant isoforms CD44v4, CD44v6, and CD44v9 in diffuse large B cell lymphoma (DLBCL)

CD44s CD44v6 CD44v9
Lymphoma subtype 10–20% 20–70% >70% 10–20% 20–70% >70% >70%
Positive cases out of evaluable cases are shown.
ABC, activated B cell-like; FL, follicular lymphoma; GC, germinal centre B cell-like; SLL, small lymphocytic lymphoma.
All de novo DLBCLs 12/73 19/73 28/73 14/75 5/75 4/75 15/79
DLBCL ABC type 8/23 5/23 10/23 5/22 2/22 2/22 4/22
DLBCL GC type 4/22 8/22 7/22 2/22 2/22 0/22 7/22
Transformed FL 0/6 1/6 3/6 0/6 0/6 0/6 0/6
Transformed SLL 1/2 1/2 0/2 0/2 1/2 0/2 1/2

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