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J Clin Pathol 56:56-63 doi:10.1136/jcp.56.1.56
  • Original article

p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep™ smears

Table 3

Results of immunocytochemical analysis of p16INK4A

Score
N 0 1 2 3
Score: 0, no positive staining; 1, <10% positive staining; 2, >10% but <50% positive staining); 3, >50% positive staining. Examples of 0, 1, 2, and 3 are shown in fig 3A–D.
CIN, cervical intraepithelial neoplasia; cGIN, cervical glandular intraepithelial neoplasia.
Normal 21 21 (100%) 0 (0%) 0 (0%) 0 (0%)
cGIN 5 0 (0%) 0 (0%) 1 (20%) 4 (80%)
CIN 1 38 0 (0%) 3 (8%) 11 (29%) 24 (63%)
CIN 2 33 0 (0%) 9 (27%) 9 (27%) 15 (46%)
CIN 3 46 1 (2%) 3 (7%) 14 (30%) 28 (61%)
Invasive 10 0 (0%) 0 (0%) 0 (0%) 10 (100%)

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