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J Clin Pathol 55:591-595 doi:10.1136/jcp.55.8.591
  • Original article

Acute lymphoblastic leukaemia of the L3 subtype in adults in the Northern health region of England 1983–99

Table 1

Patient details including immunophenotypic and cytogenetic analysis

Patient Sex/Age Immunophenotype CR Survival (weeks) Cytogenetic analysis
B, B lineage markers; CR, complete remission; ND, not done; SIg, surface immunoglobulin.
Cytogenetic abnormalities referred to in the text are highlighted in bold.
1 F/66 B+, SIg+ + Alive 46,XX,t(8;14)(q24;q32)
2 M/40 B+, SIg+ 5 days 46,XY,t(8;14)(q24;q32)
3 M/79 B+, Sig+ 1 46,XY,t(8;14)(q24;q32)
4 F/46 B+, Sig+ 12 46,XX,t(8;14)(q24;q32)/46,idem,dup(1)(q?21q?32)
5 F/58 B+, SIg+ + Alive 46,XX,t(8;14)(q24;q32)/46,idem,der(4)t(1;4)(q1?;q3?),der(22)t(7;22)(q11;p1?)
6 M/55 ND 4 days 46,XY,t(8;14)(q24;q32)/46,idem,dup(1)(q2?q32)
7 F/36 B+, SIg− 13 47,XX,t(8;14)(q24;q32),add(12)(p13)
8 F/62 B+, SIg− 15 46,XX,del(6)(q?),t(8;14)(q24;q32)/45,idem,−19
9 F/83 ND 1 55−56,XX,+X,+X,+add(1)(p10),del(1)(q10),+7,t(8;14)(q24;q32),+11,del(16)(q?),+21,+21
10 M/32 B+, SIg+ 1 46,XY,dup(1)(q?25),t(3;22)(q29;q11),t(8;14)(q24;q32) /idem,add(14)(p11)
11 F/62 B+ 4 days 47,XX,t(2;8)(p12;q24),+7,t(14;18)(q32;q21)
12 M/41 B+, SIg+ + 41 47,XY,add(1)(p36),add(3)(q2?3;?),+7,t(14;18)(q32;q22),t(15;22)(q26;q21),der(19)t(1;19)(q23;p13)
13 F/72 B+, SIg+ 1 47,XX,t(14;18)(q32;q21),+7
14 M/42 B+, SIg+ + 40 50,XY,t(14;18)(q32;q21),+der(X)t(X;1)(p11;q2?1),add(4)(p1),+7,add(7)(q22),ins(8;?)(q22−4?),add(11)(q23),+12,+20
15 M/69 B+, SIg+ 3 47,XY,+12,t(14;18)(q32;q22)
16 M/76 ND + 16 46,XY,dup(1)(q21;q32),add(14)(q32)/48,idem,+7,+12/47,idem,+12,der(13)t(7;13)(q12;q32)
17 F/66 B+, SIg+ 5 days 45,XX,add(11)(q2?),der(13)t(13;22)(q32;q11?),add(14)(q32),der(19)t(12;19)(q13;p13.3),−22
18 F/89 B+ 2 days 48,X,−X,−1,−3,del(6)(q1.?5),+add(7)(p?),+i(8)(p21),+9,+11,−13,−14,+15,−16,+add(18)(q22),+19,−20,−20,−21,+4
19 M/46 ND + 50 46,XY,del(9)(p21)/46,idem,+1,der(1;6)(q10;p10)/46,idem,+der(1)?i(1)(q10)
20 M/20 B+ + 20 46,XY
21 M/53 B+ + 40 Failed analysis
22 M/53 ND 11 ND
23 F/39 B+, SIg+ + 51 ND
24 F/77 B+, SIg+ 4 days ND

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