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J Clin Pathol 55:921-925 doi:10.1136/jcp.55.12.921
  • Original article

Thrombospondin 1 protein expression relates to good prognostic indices in ductal carcinoma in situ of the breast

Table 1

Stromal thrombospondin 1 (TSP-1) expression according to histological features and p53

DCIS characteristics Stromal TSP-1 p Value
Histological grade
    Low/intermediate 9/19 (47%) 0.1154 (NS)
    High 9/39 (23%)
Necrosis
    None/focal 14/29 (48%) 0.0106
    Extensive 4/29 (14%)
Periductal inflammation
    None/mild 14/32 (44%) 0.0417
    Pronounced 4/26 (15%)
p53
    Negative 16/44 (36%) 0.0874 (NS)
    Positive 1/13 (8%)

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