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J Clin Pathol 55:834-840 doi:10.1136/jcp.55.11.834
  • Original article

Specific p53 immunostaining patterns are associated with smoking habits in patients with oral squamous cell carcinomas

Table 3

p53 expression pattern of oral carcinomas, according to smoking and alcohol drinking habits of the patients

Tobacco Alcohol
p53 expression Non-smoker (n=10*) Smoker (n=17*) p Value Non-drinker (n=6*) Drinker (n=19*) p Value
*Excluding p53 negative cases (see methods).
<50% positive cells* (n=14) 9 (64%) (90%) 5 (36%) (29%) 5 (42%) (83%) 7 (58%) (37%)
0.004 0.07
>50% positive cells (n=13) 1 (8%) (10%) 12 (92%) (71%) 1 (8%) (17%) 12 (92%) (63%)

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