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J Clin Pathol 55:69-71
  • Short report

New criteria for the differentiation between transudates and exudates

Table 2

Fluids classified into exudates and transudates using clinical diagnosis and by analysis of fluid and serum total protein, lactate dehydrogenase (LDH), and cholesterol

Clinical diagnosis N Fluid total protein Fluid cholesterol Fluid LDH Fluid: serum total protein Fluid LDH + fluid:serum total protein Light's criteria
*One case of systemic lupus erythematosus, one case of pelvic abscess, and one case of reactive pleural thickening; †includes two patients with both CCF and chronic renal failure and one with both CCF and hypoalbuminaemia.
CCF, congestive cardiac failure; FN, false negative; FP, false positive; TN, true negative; TP, true positive.
TP FN TP FN TP FN TP FN TP FN TP FN
Exudates total 30 25 5 26 4 27 3 27 3 30 0 27 3
Malignancy 22 19 3 19 3 20 2 20 2 22 0 19 3
Infection 5 3 2 4 1 4 1 4 1 5 0 5 0
Other* 3 3 0 3 0 3 0 3 0 3 0 3 0
TN FP TN FP TN FP TN FP TN FP TN FP
Transudates total† 24 18 6 16 8 19 5 19 5 17 7 16 8
CCF 13 7 6 7 6 10 3 9 4 11 2 8 5
Cirrhosis 6 6 0 6 0 6 0 6 0 6 0 5 1
Renal failure 4 2 2 2 2 3 1 4 0 4 0 3 1
Hypoalbuminaemia 4 4 0 3 1 2 2 3 1 3 1 2 2

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