Table 3
Genotype distribution for tumour necrosis factor α (TNF-α) promoter polymorphisms at positions −308 and −238 in Helicobacter pylori infected patients with carcinoma and benign disease
| ureA+ | |||
|---|---|---|---|
| Locus | Genotype | Carcinoma (n = 37) | Benign disease (n = 25) |
| −308 | G/G | 32 (86.5%) | 20 (80%) |
| G/A | 4 (10.8%) | 5 (20%) | |
| A/A | 1 (2.7%) | 0 | |
| Allele frequencies for −308A | 0.0811 | 0.1 | |
| −238 | G/G | 35 (94.6%) | 23 (92%) |
| G/A | 2 (5.4%) | 2 (8%) | |
| A/A | 0 | 0 | |
| Allele frequencies for −238A | 0.027 | 0.04 | |
