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J Clin Pathol 54:652-654 doi:10.1136/jcp.54.8.652

Apolipoprotein E alleles in women with pre-eclampsia

Table 1

Apolipoprotein E allele frequencies and genotype among women with pre-eclampsia and healthy pregnant controls, and in the general population

Allele frequencies Pre-eclamptic women (%) Controls (%) Population (%)
ε2 14/133 (5.3%) 11/91 (6.0%) 4%
ε3 203/133 (76.3%) 137/133 (75.3%) 77%
ε4 49/133 (18.4%) 34/133 (18.7%) 19%
Genotype frequencies
2/2 0/133 (0%) 0/91 (0%) 0.3%
2/3 11/133 (8.3%) 10/91 (11.0%) 5.4%
2/4 3/133 (2.3%) 1/91 (1.1%) 1.8%
3/3 79/133 (59.4%) 54/91 (59.3%) 58.7%
3/4 34/133 (25.6%) 19/91 (20.9%) 30.6%
4/4 6/133 (4.5%) 7/91 (7.7%) 3.2%

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