Table 1
Clinical characteristics
| Patient | Age (years) | Sex | Clinical picture | Chest x ray | CT chest | Bone marrow | Protein studies | Cardiac studies | Neurological findings | Survival (years) |
|---|---|---|---|---|---|---|---|---|---|---|
| LUL, left upper lobe; RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe; LLL, left lower lobe; CT, computed tomography; ECG, electrocardiogram; echo, echocardiogram; LVEF, left ventricular ejection fraction; LVH, left ventricular hypertrophy; PVCs, premature ventricular contractions; MR, mitral regurgitation; TR, tricuspid regurgitation. | ||||||||||
| 1 | 45 | F | Non-productive cough | Nodular density in LUL and RUL | 10 bilateral pulmonary nodules; no adenopathy | Normocellular | Polyclonal gammopathy with no monoclonal spike | Normal ECG. Normal echo with LVEF 61% | Atypical trigeminal neuralgia | 6+ |
| 2 | 85 | F | Non-productive cough | Right hilar mass, RML mass, RLL mass, left lingular mass | Multiple pulmonary nodules, bilateral | Normocellular | Not done | ECG: old anterior septal infarct. Echo: severe concentric LVH | None | Died at 5 years of unknown cause |
| 3 | 74 | F | Generalised weakness, fatigue | RLL/anterior mediastinal mass | 4 × 5 cm pulmonary nodule in anterior mediastinum | Normocellular | Not done | ECG: occasional PVCs | None | Large cell transformation after 3 years; died within following year |
| 4 | 77 | F | Weight loss | Multiple densities in right lung | Four nodules in RUL, two nodules in left lung | Not done | Polyclonal gammopathy with no monoclonal spike | Normal ECG. Normal echo with normal LV function, mild MR, trivial TR | None | 9+ |
| 5 | 68 | F | Asymptomatic | Solitary pulmonary nodule in RLL and diffuse interstitial infiltrates | 2 cm mass in posterior RLL | Normocellular | No monoclonal spike | Normal ECG. Echo: normal LVEF (65–70%), pulmonary hypertension | None | 3+ |
| 6 | 58 | F | Asymptomatic | Three pulmonary nodules in LLL | Three nodules in posterolateral segments of LLL | Normocellular | No monoclonal protein | Normal ECG | Post thoracotomy chronic pain syndrome with neuroma formation | 8+ |
