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J Clin Pathol 54:608-612 doi:10.1136/jcp.54.8.608

Erythroleukaemia in the north of England: a population based study

Table 2

Abnormal karyotypes

Age Karyotype Curative treatment? CR? Overall survival (months)
CR, complete remission.
Standard risk
3 47,XY,+21c[4]/48,XY,+11,+21c[6] Yes Yes 42+
33 46,XY,del(9)(q13q22)[8]/46,XY[12] Yes Yes 8
66 46,XY,del(11)(q14-21)[9]/46,XY[1] Yes Yes 49+
72 47,XY,+8[11] No No 8
Poor risk
39 46,XX,add(3)(q2?6)[4]/46,idem,-7[6]/46,XX[1] Yes No 18
39 42-45,XY,-3,-5,-7,+8,add(10)(p11-12),der(16)(q22),-17,der(17), t(7;17)(q11;q22-24)[cp10] Yes Yes 7
45 44,XY,-3,-5,-6,del(7)(q2?2),+8,?t(9;9)(p?;p?),-13,-15,del(20)(q1?1),+mar1,+mar2,inc[cp3] Yes No 2
53 42-44,der(1),der(3),der(7),der(16),der(19),inc[7] Yes No 4
57 46,XX,del(5)(q12q31)[2]/44-46,idem,add(1)(q?),-3,add(7)(q?),add(16)(q?), -17,+mar,inc[]/46,XX[] Yes No 0
61 44,XY,der(1)t(1;?16)(p1?;?q10),+del(1)(q1?),del(3)(q2?3q2?6), del(5)(q31q3?5),-7,-16,?del(20)(p1?3)[9] Yes No 0
64 46-54,XY,del(1)(q?),+4,-5,+?6x2,+8,+t(11;?22)(?q10;?q10)x2,-16,-17, t(17;22)(p?10;q?),+19,+idic(22)(q13)x2[cp5]/46,XY[2] Yes No 15
64 45,XX,add(1)(q?42),del(1)(q?32),der(5),der(7),del(7)(p22p15)inv(7)(p15q22),-19[13] Yes No 0
68 46-47,XY,-1,dic(5;7)(q14;q32),der(17)?t(1;17)(p22;q24),add(18)(q2?3),add(19)(p1?),?idic(21)(p1?)?add(22)(p11),+2∼4mar[cp5] Yes Yes 5+
69 44-45,t(1;17)(q?;q?),der(1),add(3)(p?),der(5),add(16)(p?),inc[20]/46,XY[4] Yes No 0
72 40-46,X,der(3)?t(2;3),-5,-5,del(6)(q?),-7,add(18)(q2?),-20,inc[cp9]/46,XX[1] No No 7
84 68-75,XXX,-1,del(1)(p3),del(2)(p?),+del(2)(p?),+3,add(3)(q?),del(6)(q2),+del(6)(q2),add(11)(q23),+?dup(11)(q13q24),+6mar[cp14]/46XX[4] No No 0

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