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J Clin Pathol 54:476-480 doi:10.1136/jcp.54.6.476

The usefulness of antibodies to the BRCA1 protein in detecting the mutated BRCA1 gene. An immunohistochemical study

Table 3

BRCA1 immunostaining in BRCA1 negative cases

Familial cases (n = 16) Sporadic cases (n = 22)
Nuclear staining Cytoplasmic staining Nuclear staining Cytoplasmic staining
Antibody Positive Negative Positive Negative Positive Negative Positive Negative
D-20 16 16 22 22
I-20 11 5 15 1 9 13 22
K-18 16 5 11 22 2 20
Ab-1 6 10 16 11 11 1 21

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