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J Clin Pathol 54:470-473 doi:10.1136/jcp.54.6.470

Dimethylarginines in chronic renal failure

Table 1

Serum concentrations of dimethylarginine and arginine in healthy subjects and in patients with renal failure

Serum concentration (μmol/l)
ADMA SDMA Arginine
Results are mean (SD).
*p <0.01 and **p <0.000. Significantly different from healthy controls.
†p <0.01. Significantly different from predialysis values by paired t test.
ADMA, asymmetrical dimethylarginine; SDMA, symmetrical dimethylarginine.
Healthy subjects (n = 9) 0.61 (0.13) 0.41 (0.12) 118 (17.5)
Predialysis (n = 17) 0.99 (0.25)** 4.53 (1.54)** 116 (25.2)
Post dialysis 0.63 (0.15)† 2.95 (1.06)*† 104 (26.7)
CAPD (n = 9) 0.96 (0.31)* 4.01 (2.22)* 128 (23.6)
CRF (n = 13) 1.04 (0.17)* 2.47 (0.95)* 125 (27.8)

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