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J Clin Pathol 54:309-313 doi:10.1136/jcp.54.4.309

Predictive value of topoisomerase IIα immunostaining in urothelial bladder carcinoma

Table 3

Cox's regression analysis for independent prognostic variables with respect to patients' specific survival (dependent variable)

Variables in the equation
Variable B SE Wald df p Value
Total number of cases was 94.
Df, degrees of freedom; CI, confidence interval.
Age 0.0569 0.0270 4.4488 1 0.0349
Sex 0.3503 0.4979 0.4948 1 0.4818
Stage 2.3819 0.5122 21.6222 1 0.0000
Grade 1.5214 0.6122 6.1753 1 0.0130
Topoisomerase IIα 1.3813 0.4883 8.0031 1 0.0047
p53 0.0757 0.2389 0.1004 1 0.7514
Bcl-2 0.7219 0.4737 2.3225 1 0.1275
Ki-67 0.1975 0.2427 0.6622 1 0.4158
95% CI for Exp (B)
Variable Exp (B) Lower Upper
Age 1.0585 1.0040 1.1160
Sex 1.4194 0.5349 3.766
Stage 10.8255 3.9667 29.5438
Grade 4.5786 1.3791 15.2007
Topoisomerase IIα 3.9802 1.5285 10.3638
p53 1.706 0.6752 1.7228
Bcl-2 2.0583 0.8134 5.2082
Ki-67 1.2183 0.7572 1.9603

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