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J Clin Pathol 54:285-292 doi:10.1136/jcp.54.4.285

Interleukin 10 in Helicobacter pylori associated gastritis: immunohistochemical localisation and in vitro effects on cytokine secretion

Table 2

Expression of interleukin 10 (IL-10) protein by gastric epithelium and lamina propria mononuclear cells (LPMNCs) in Helicobacter pylori positive (chronic gastritis) and H pylori negative (normal mucosa) patients

Helicobacter pylori +ve Helicobacter pylori −ve
*No significant difference between H pylori +ve v H pylori −ve.
**Proportion of LPMNCs stained for IL-10 protein: p < 0.05 for H pylori +ve v H pylori −ve (Fisher's exact test) using pooled values (scores 0–1 and 2–3).
No. of cases studied 13 16
Epithelium*
Absent (0) 0 3
Weak (1) 1 3
Moderate (2) 7 8
Strong (3) 5 2
LPMNCs**
Absent (0) 0 4
<10% (1) 1 5
10–50% (2) 11 7
>50% (3) 1 0

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