rss
J Clin Pathol 54:249-252 doi:10.1136/jcp.54.3.249

Evidence for loss of heterozygosity of 5q in sporadic haemangiomas: are somatic mutations involved in haemangioma formation?

Table 3

Number of informative marker lesion combinations, and number of loss of heterozygosity (LOH) events seen for each chromosomal location

No. of LOH events (total number of informative combinations)
Chromosomal location UK1 UK2 US1 US2 US3 US4 Total no. of informative marker/lesion combinations Total no. of informative LOH events seen
This information is given for each haemangioma successfully analysed, as well as for the total data set.
*A significantly greater (p <0.05) proportion of LOH events for markers on chromosome 5q than for markers on either chromosome 9 or chromosome 5p (using the χ2 test with 1 degree of freedom).
9 0 (9) 0 (6) 3 (6) 1 (4) 25 4
5p 0 (3) 2 (5) 0 (2) 0 (2) 0 (2) 1 (4) 18 3
5q 1 (9) 4 (9) 3 (6) 1 (4) 5 (7) 5 (8) 43 19*
Total 87 26

This Article

Latest from JCP Education

Latest from JCP Education

Register for free content


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of JCP.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

  • Latest Pathology jobs

    Latest Pathology jobs