rss
J Clin Pathol 54:229-235 doi:10.1136/jcp.54.3.229

Expression of cyclins and cyclin dependent kinases in human benign and malignant melanocytic lesions

Table 3

Number of positively stained tissue sections in each category divided into melanocytic naevi, low risk primary (<1.5 mm), intermediate to high risk primary melanomas (>1.5 mm), and metastases

0–5% 6–25% 26–50% 51–75% 76–100%
Cyclin A Naevi 9 3 0 0 0
<1.5 mm 18 4 0 0 0
>1.5 mm 15 7 1 0 0
Metastases 15 3 0 0 0
Cyclin B1 Naevi 5 3 4 0 0
<1.5 mm 13 6 3 0 0
>1.5 mm 12 7 4 0 0
Metastases 5 0 7 2 2
Cyclin D1 Naevi 4 7 1 0 0
<1.5 mm 13 7 2 0 0
>1.5 mm 6 12 5 0 0
Metastases 10 4 1 0 0
Cyclin D2 Naevi 5 4 2 1 0
<1.5 mm 19 2 0 0 0
>1.5 mm 19 1 1 0 0
Metastases 7 6 0 0 0
Cyclin D3 Naevi 5 2 3 1 0
<1.5 mm 11 6 5 0 0
>1.5 mm 11 6 2 2 0
Metastases 3 3 7 3 1
Cyclin E Naevi 1 3 1 2 5
<1.5 mm 2 15 2 2 0
>1.5 mm 3 3 5 1 9
Metastases 0 0 2 0 14
CDK1 Naevi 4 4 3 0 0
<1.5 mm 12 8 1 0 0
>1.5 mm 12 3 4 1 1
Metastases 8 4 2 3 0
CDK2 Naevi 4 5 2 0 1
<1.5 mm 0 4 14 3 1
>1.5 mm 3 5 3 3 8
Metastases 0 3 2 7 5
CDK4 Naevi 0 3 4 3 1
<1.5 mm 7 3 11 1 0
>1.5 mm 7 5 3 3 2
Metastases 7 3 3 2 1

This Article

Latest from JCP Education

Latest from JCP Education

Register for free content


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of JCP.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

  • Latest Pathology jobs

    Latest Pathology jobs