Increasing recognition of haemoglobin Le Lamentin
- K Wiener1,
- X McFarlane2,
- B N Green3
- 1Department of Clinical Biochemistry, North Manchester General Hospital, Manchester, M8 5RB, UK
- 2Department of Gastroenterology, North Manchester General Hospital
- 3Micromass UK Ltd, 3 Tudor Road, Altrincham, Cheshire WA14 5RZ, UK
The haemoglobin variant Le Lamentin (α20 His → Gln) was first described in 1982 in a negro family in the French West Indies.1 Subsequently, it has been reported in a Japanese family2 and in a Spanish family,3 and recently it was found in a British white man whose haemoglobin displayed an unusual peak when his blood was being assayed for glycated haemoglobin (haemoglobin A1c) by high performance liquid chromatography (HPLC).4 …









