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J Clin Pathol 54:860-865

Loss of DCC expression in astrocytomas: relation to p53 abnormalities, cell kinetics, and survival

Table 1

Univariate analysis of prognostic factors for astrocytomas

Factor Category n Log rank c2 p Value Favourable feature
n, number of cases; DCC, deleted in colorectal cancer; LI, labelling index; MI, mitotic index; AI, apoptotic index.
Grade II 25 22.919 <0.0001 Grade II
III 24
IV 19
DCC score ≥3 41 4.346 0.037 High score
≤4 27
p53 LI (%) >40 22 5.330 0.021 Low value
≤40 46
Ki-67 LI (%) >30 21 13.004 0.0003 Low value
≤30 47
MI (%) >0.40 19 20.795 <0.0001 Low value
≤0.40 49
AI (%) >0.40 14 5.032 <0.0001 Low value
≤0.40 54
DCC score ≥3 p53 LI >40 31 15.105 0.002 DCC score ≤4
DCC score ≥3 p53 LI ≤40 10 p53 LI >40
DCC score ≤4 p53 LI >40 15
DCC score ≤4 p53 LI ≤40 12

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