Table 2
Conditions associated with subnormal neutrophil chemotaxis
| Defects in the neutrophil |
| Neonatal neutrophils |
| Neutrophil actin dysfunction |
| Syndromes: Schwachman, glycogenosis type 1b, Chediak Higashi, and hyper-Ig E |
| Acrodermatitis enteropathica (zinc deficiency) |
| Specific granule deficiency |
| Chromosome 7 abnormalities |
| Direct inhibition of neutrophil chemotaxis |
| Juvenile periodontitis |
| Immune complex diseases |
| Wiskott Aldrich syndrome |
| Bone marrow transplant |
| Drugs such as corticosteroids, amphotericin B, antithymocyte globulin |
| Granulomatous diseases such as sarcoidosis |
| Malignancies |
| Defective generation of chemotactic factors |
| Familial complement deficiencies of alternative or classical pathway |
