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J Clin Pathol 53:676-684 doi:10.1136/jcp.53.9.676

Recent striking changes in histological differentiation and rate of human papillomavirus infection in squamous cell carcinoma of the lung in Okinawa, a subtropical island in southern Japan

Table 5

Histological differentiation of squamous cell carcinoma (SCC) and detection of human papillomavirus (HPV) by the polymerase chain reaction (PCR) and non-isotopic in situ hybridisation (NISH) in 1995–8

Case no. Sex Age Histological differentiation Detected type of HPV by PCR NISH
PCR was carried out using the primers in table 1.
*Was not detected by the use of the type specific primers .27
f, female; m, male; M, moderately differentiated; P, poorly differentiated; W, well differentiated.
Histological differentiation of SCC and detection of HPV by PCR and NISH in 1995
1 m 67 W 6*, 18 18
2 m 62 W 16 16
3 m 70 W 6*, 18 18
4 m 74 W 6*, 11 11
5 m 68 W 16 16
6 m 72 W 11 11
7 m 66 W 11*, 16 16
8 f 73 W 16 16
9 m M 6*
10 m 73 M 11 11
11 m 87 M
12 m 64 M 18 18
13 m 73 M 11 11
14 f M 18 18
15 m 68 M
16 f 75 M
17 m 44 M 16 16
18 f 73 M
19 m 67 M 11 11
20 m 73 M 6 6
21 m M
22 m 66 M 18 18
23 m M 6 6
24 m 75 M 16*
25 m 63 M 11 11
26 m 64 M
27 m 69 M
28 m 66 P 6*
29 m P 6* 6
30 m 68 P
31 m 70 P
32 m 70 P 11 11
33 m 73 P
34 m 78 P
Histological differentiation of SCC and detection of HPV by PCR and NISH in 1996
1 m 66 W
2 f W 11 11
3 f 73 W 18 18
4 m 69 W 6 6
5 f 64 W 18 18
6 m 54 W 18 18
7 m 83 W
8 m 53 W 6 6
9 m 67 M
10 m 62 M
11 m M
12 m 66 M 16 16
13 m 87 M 16*, 18 16
14 m 64 M 11*
15 m 73 M 11 11
16 m 68 M
17 m 70 M
18 f 75 M 6 6
19 m 44 M
20 f 74 M
21 f 73 M
22 m 67 M
23 m 68 M
24 m 73 M
25 m M
26 m 65 M
27 m M
28 m 75 M
29 m 73 P
30 m 72 P
31 m P 16*, 18 18
32 m 68 P
33 m 70 P
34 m 70 P
35 m 73 P 18 18
36 m 63 P
37 m 78 P
Histological differentiation of SCC and detection of HPV by PCR and NISH in 1997
1 m 76 W 16, 18* 16
2 m 63 W 11 11
3 m 80 W 16 16
4 m 69 W
5 m 71 M
6 m M 18 18
7 m 67 M
8 m 68 M
9 f 67 M 11 11
10 m 82 M
11 m 68 M
12 m 68 M
13 m 73 M
14 m 72 M
15 f 77 M
16 m 68 M
17 m 70 M
18 m 82 P
19 f 65 P
20 m 83 P
21 m 67 P
22 m P
Histological differentiation of SCC and detection of HPV by PCR and NISH in 1998
1 m W 11 11
2 f W 11*
3 m W
4 m W
5 m W 18 18
6 f M
7 m M 11 11
8 m M
9 m M
10 m M
11 m M
12 m M
13 f M 6 6
14 m M
15 m M
16 f M
17 m M
18 m P
19 f P
20 m P
21 m P

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