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J Clin Pathol 53:606-611 doi:10.1136/jcp.53.8.606

PCR based high risk HPV testing is superior to neural network based screening for predicting incident CIN III in women with normal cytology and borderline changes

Table 8

Morphological markers associated with HPV v high risk HPV test result

High risk HPV
Positive (n = 121) Negative (n = 610)
Morphological marker present n % n %
HPV, human papillomavirus.
Nuclear and cytoplasmatic enlargement 4 3.3 22 3.6
Multinucleation 5 4.0 41 6.7
Koilocytosis 5 4.0 21 3.4
Parakeratosis 4 3.3 26 4.3
(Mildly) hyperchromatic nucleus 1 0.8 3 0.5
Atypical reserve cell hyperplasia 4 3.3 6 1.0
Immature squamous metaplasia 1 1.7 14 2.3
Any marker present 14 12 79 13

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