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J Clin Pathol 53:591-595 doi:10.1136/jcp.53.8.591

Small cell malignant melanoma: a variant of naevoid melanoma. Clinicopathological features and histological differential diagnosis

Table 2

Histological criteria for the diagnosis of small cell melanoma

(1) An obvious intraepidermal component recognisable at low power as in situ melanoma
(2) An intradermal component composed entirely of small dark cells mimicking benign naevus cells, usually lying in tightly packed nests
(3) The dermal nests composed of cells with hyperchromatic, slightly pleomorphic nuclei and scanty cytoplasm. There may be occasional prominent nucleoli
(4) A stromal response of proliferation of small blood vessels between the dermal nests and a variable lymphocytic infiltrate

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