Table 4
Kruskall-Wallis analysis of variance of inter-related histological scores
| Portal inflammation by.. | Piecemeal necrosis by.. | Lobular inflammation by.. | Councilman bodies by.. | Macrophage reaction by | Fibrosis stage by.. | HBcAg by.. | Ground glass cells by.. | Steatosis by.. | Log serum HBV DNA by.. | |
|---|---|---|---|---|---|---|---|---|---|---|
| The numbers denote the significance levels of the χ2 statistic, corrected for ties. The row variables are the grouping variables, the columns the dependent variables. | ||||||||||
| For ground glass cells the patients with a score of 1 are compared with the other patients (scores 0, 2, or 3). | ||||||||||
| HBcAg, hepatitis B core antigen; HBV, hepatitis B virus. | ||||||||||
| Portal inflammation | 85.1 | 35.2 | 41.5 | 10.8 | 54.1 | 35.2 | 5.9 | 5.5 | 24.5 | |
| <0.00005 | <0.00005 | <0.00005 | 0.0127 | <0.00005 | <0.00005 | 0.1150 | 0.1404 | <0.00005 | ||
| Piecemeal necrosis | 80.6 | 14.0 | 29.9 | 5.9 | 78.5 | 42.5 | 11.4 | 2.2 | 26.6 | |
| <0.00005 | 0.0030 | <0.00005 | 0.1150 | <0.00005 | <0.00005 | 0.0097 | 0.5283 | <0.00005 | ||
| Lobular inflammation | 32.8 | 15.3 | 80.3 | 8.9 | 5.6 | 7.6 | 8.2 | 6.1 | 9.3 | |
| <0.00005 | 0.0016 | <0.00005 | 0.0305 | 0.1339 | 0.0547 | 0.0414 | 0.1079 | 0.0259 | ||
| Councilman bodies | 43.1 | 30.0 | 80.2 | 11.6 | 15.9 | 25.6 | 8.9 | 4.8 | 12.8 | |
| <0.00005 | <0.00005 | <0.00005 | 0.0088 | <0.00005 | <0.00005 | 0.0311 | 0.1850 | 0.0050 | ||
| Macrophage reaction | 8.4 | 6.2 | 7.9 | 8.9 | 3.4 | 8.0 | 1.8 | 1.5 | 5.1 | |
| 0.0151 | 0.0441 | 0.0196 | 0.0114 | 0.1785 | 0.0180 | 0.4099 | 0.4778 | 0.0763 | ||
| Fibrosis stage | 56.2 | 80.4 | 17.3 | 20.9 | 6.1 | 21.1 | 16.6 | 4.6 | 23.8 | |
| <0.00005 | <0.00005 | 0.0017 | 0.0003 | 0.1953 | 0.0003 | 0.0023 | 0.3270 | 0.0001 | ||
| HBcAg expression | 34.4 | 41.8 | 7.8 | 22.7 | 7.7 | 21.8 | 9.1 | 4.8 | 32.7 | |
| <0.00005 | <0.00005 | 0.0996 | 0.0001 | 0.1046 | 0.0002 | 0.0578 | 0.3044 | <0.00005 | ||
| Ground glass cells | 5.8 | 8.8 | 4.5 | 4.7 | 1.4 | 5.9 | 5.2 | 1.1 | 2.0 | |
| 0.0162 | 0.0029 | 0.0334 | 0.0366 | 0.2410 | 0.0150 | 0.0223 | 0.2989 | 0.1561 | ||
| Steatosis | 6.8 | 9.2 | 4.5 | 6.9 | 1.1 | 6.1 | 3.7 | 1.3 | 6.11 | |
| 0.0330 | 0.0099 | 0.1064 | 0.0314 | 0.5686 | 0.0467 | 0.1568 | 0.5210 | 0.0471 | ||
