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J Clin Pathol 53:302-307 doi:10.1136/jcp.53.4.302

Dietary calcium supplementation increases apoptosis in the distal murine colonic epithelium

Table 2

Number of nuclei in each hemicrypt and relative position of apoptotic cells

Nuclei/hemicrypt Crypt position
Results are expressed as mean (SEM).
Relative crypt position refers to the percentage distance along crypt length: 0, crypt base; 100, crypt surface.
*p = 0.001 v calcium distal colon.
†p = 0.01 v calcium distal colon.
‡p = 0.003 v calcium proximal colon.
¶p = 0.03 v calcium proximal colon.
Control group
Proximal 24.3 (0.73)* 39.5 (1.9)‡
Distal 22.6 (0.46)† 37.1 (2.8)
Calcium supplemented group
Proximal 20.9 (0.37) 31.6 (1.0)
Distal 21.0 (0.36) 35.8 (1.4)¶

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