HLA-DR and β₂ microglobulin expression in medullary and atypical medullary carcinoma of the breast: histopathologically similar but biologically distinct entities

Table 2

Major histocompatibility antigen immunostaining by tumour type

	Tumour type
Variable	IDC without LI	IDC with LI	ATMC	MC	p Value
Values are means. ^A,B Pairwise comparisons. Means with different letters are significantly different (p ≤ 0.05).
ATMC, atypical medullary carcinoma; IDC, invasive duct carcinoma; LI, lymphocytic infiltrate; MC, medullary carcinoma.
HLA-DR in tumour (%)	0.10^A	0.10^A	0.33^A	2.4^B	0.001
HLA-DR in tumour (intensity)	0.20^A	0.10^A	0.33^A	1.80^B	0.0006
β₂ Microglobulin in tumour (%)	0.00^A	1.2	1.33	2.4^B	0.011
β₂ Microglobulin in tumour (intensity)	0.00^A	0.80^A	0.83^A	1.80^B	0.0057
HLA-DR in LI	–	1.10	0.67	1.60	0.35
β₂ Microglobulin in LI	–	2.20	1.50	2.80	0.15

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HLA-DR and β₂ microglobulin expression in medullary and atypical medullary carcinoma of the breast: histopathologically similar but biologically distinct entities

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HLA-DR and β₂ microglobulin expression in medullary and atypical medullary carcinoma of the breast: histopathologically similar but biologically distinct entities