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J Clin Pathol 53:191-196 doi:10.1136/jcp.53.3.191

Completeness of excision and follow up cytology in patients treated with loop excision biopsy

Table 5

Odds ratios for incompleteness of excision compared with the status of follow up cytology in loop biopsies, CIN3

Incompleteness of excision Odds ratio Confidence interval p Value
Confidence limits used: *Cornfield 95% confidence limits; **Exact 95% confidence limits. CIN, cervical intraepithelial neoplasia.
Residual lesion
Ectocervical margin 6.60 1.25 < OR < 42.99** 0.004
Endocervical margin 1.48 0.03 < OR < 18.65** NS
Ecto- and endocervical margins 8.69 0.69 < OR < 77.97** 0.006
Glands 4.49 0.59 < OR < 33.92** 0.05
Deep margin 33.67 3.95 < OR < 268.80** 0.00000000
Equivocal 20.72 4.17 < OR < 130.95** 0.00000001
Recurrent lesion
Ectocervical margin 0.69 0.20 < OR < 2.18* NS
Endocervical margin 2.32 1.04 < OR < 5.12* 0.02
Ecto- and endocervical margins 2.83 0.87 < OR < 8.68* 0.04
Glands 1.17 0.41 < OR < 3.17* NS
Deep margin 8.78 2.63 < OR < 28.61* 0.000003
Equivocal 3.15 1.14 < OR < 8.44* 0.009
Persistent lesion
Ectocervical margin 3.96 0.52 < OR < 29.90** NS
Endocervical margin 4.44 0.58 < OR < 33.55** 0.049
Ecto- and endocervical margins 4.34 0.08 < OR < 55.62** NS
Glands 5.99 0.99 < OR < 41.36** 0.009
Deep margin 22.44 1.68 < OR < 209.52** 0.000004
Equivocal 20.72 4.17 < OR < 130.95** 0.00000001

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