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J Clin Pathol 53:89-94 doi:10.1136/jcp.53.2.89

ACP Best Practice No. 155. Guidelines for handling oesophageal biopsies and resection specimens and their reporting

Table 3

TNM clinical classification 31

T: Primary tumour
T1 Tumour invades lamina propria or submucosa
T2 Tumour invades muscularis propria
T3 Tumour invades adventitia
T4 Tumour invades adjacent structures
N: Regional lymph nodes
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Regional lymph node metastasis
M: Distant metastasis
MX Distant metastasis cannot be assessed
M0 No distant metastasis
M1 Distant metastasis
For tumours of the lower thoracic oesophagus
M1a Metastasis in coeliac lymph nodes
M1b Other distant metastasis
For tumours of the upper thoracic oesophagus
M1a Metastasis in cervical lymph nodes
M1b Other distant metastasis
For tumours of the mid-thoracic oesophagus
M1a Not applicable
M1b Non-regional lymph node or other distant metastasis
pTNM pathological classification
The pT, pN, and pM categories correspond to the T, N, and M categories

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