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J Clin Pathol 53:131-136 doi:10.1136/jcp.53.2.131

Temporal artery biopsy: is there any value in examining biopsies at multiple levels?

Table 3

Analysis of sensitivity of economic model to assumptions of frequency of giant cell arteritis (GCA) in cases with periarterial lymphocyte infiltration (PALI) and relative costs of diagnostic strategies

Assumption (other variables held constant) Marginal cost* of strategy B compared with strategy A Marginal cost* of strategy C compared with strategy A Marginal cost* of strategy B compared with strategy C
*In Welcan units.
CL, confidence limit.
GCA at upper 95% CL of frequency in cases with PALI 21.84 7.01 38.06
GCA at observed frequency in cases with PALI 83.5 21 208.5
GCA at lower 95% CL of frequency in cases with PALI No extra cases detected No extra cases detected No extra cases detected
Strategy B costs 4 Welcan units/case (rather than 4.5) 55.67 21 125

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