Table 4
Serum VLDL, HDL2 and HDL3 apolipoprotein (apo) profiles (AU/L) in mothers and their newborns
| Mothers | Newborns | |||||||
|---|---|---|---|---|---|---|---|---|
| Group 1 | Group 2 | Group 3 | Group 4 | Group 1 | Group 2 | Group 3 | Group 4 | |
| Values are mean (SEM). | ||||||||
| Group 1, mothers with poorly controlled diabetes and macrosomic newborns. | ||||||||
| Group 2, mothers with well controlled diabetes and appropriate for gestational age newborns. | ||||||||
| Group 3, healthy mothers with macrosomic newborns. | ||||||||
| Group 4, healthy mothers with appropriate for gestational age newborns. | ||||||||
| Values within a row with different numbers of asterisks are significantly different, p < 0.05. | ||||||||
| AU/L, arbitrary units/litre of serum; on the densitometer tracing obtained after electrophoresis, the concentration of each apolipoprotein was calculated from the percentage of the area for each apolipoprotein relative to the total apolipoprotein concentration of each fraction. HDL, high density lipoprotein; VLDL, very low density lipoprotein. | ||||||||
| VLDL | ||||||||
| Apo B100 | 0.690 (0.013)* | 0.313 (0.050)** | 0.322 (0.045)** | 0.244 (0.030)** | 0.205 (0.023)* | 0.071 (0.016)** | 0.080 (0.017)** | 0.068 (0.01)** |
| Apo C-II | 0.063 (0.010 | 0.052 (0.009) | 0.063 (0.011) | 0.084 (0.012) | 0.043 (0.011) | 0.032 (0.009) | 0.036 (0.010) | 0.04 (0.008) |
| Apo C-III | 0.124 (0.021)* | 0.050 (0.010)** | 0.053 (0.008)** | 0.060 (0.010)** | 0.046 (0.012) | 0.033 (0.009) | 0.030 (0.008) | 0.029 (0.009) |
| Apo E | 0.059 (0.007 | 0.061 (0.008) | 0.060 (0.011 | 0.081 (0.011) | 0.030 (0.008) | 0.025 (0.006) | 0.031 (0.007) | 0.027 (0.006) |
| HDL 2 | ||||||||
| Apo A-I | 0.683 (0.089) | 0.723 (0.062) | 0.761 (0.057) | 0.770 (0.080) | 0.480 (0.028)* | 0.333 (0.040)** | 0.361 (0.028)** | 0.309 (0.026)** |
| Apo A-II | 0.101 (0.021) | 0.152 (0.030) | 0.130 (0.040) | 0.110 (0.040) | 0.101 (0.013)* | 0.053 (0.010)** | 0.064 (0.008)** | 0.058 (0.009)** |
| Apo C-II | 0.036 (0.008) | 0.044 (0.012) | 0.032 (0.008) | 0.043 (0.008) | 0.042 (0.010) | 0.028 (0.009) | 0.030 (0.008) | 0.034 (0.006) |
| Apo C-III | 0.054 (0.009) | 0.043 (0.008) | 0.040 (0.009) | 0.048 (0.010) | 0.033 (0.007) | 0.034 (0.005) | 0.032 (0.004) | 0.040 (0.007) |
| Apo E | 0.032 (0.007) | 0.041 (0.009) | 0.035 (0.008) | 0.032 (0.007) | 0.031 (0.008) | 0.050 (0.010) | 0.041 (0.009) | 0.053 (0.009) |
| HDL 3 | ||||||||
| Apo A-I | 0.323 (0.041)** | 0.781 (0.051)** | 0.863 (0.050)* | 0.800 (0.053)* | 0.462 (0.038)* | 0.301 (0.042)** | 0.345 (0.020)** | 0.330 (0.027)** |
| Apo A-II | 0.164 (0.024)** | 0.290 (0.040)* | 0.325 (0.033)* | 0.282 (0.027)* | 0.233 (0.044)* | 0.135 (0.020)** | 0.140 (0.021)** | 0.152 (0.030)** |
| Apo C-II | 0.073 (0.011) | 0.057 (0.012) | 0.074 (0.009) | 0.063 (0.014) | 0.049 (0.008) | 0.044 (0.007) | 0.050 (0.009) | 0.032 (0.007) |
| Apo C-III | 0.065 (0.010) | 0.063 (0.012) | 0.080 (0.008) | 0.070 (0.011) | 0.060 (0.010) | 0.072 (0.011) | 0.074 (0.012) | 0.068 (0.010) |
| Apo E | 0.056 (0.012) | 0.060 (0.010) | 0.055 (0.010) | 0.051 (0.009) | 0.037 (0.006) | 0.042 (0.009) | 0.043 (0.010) | 0.039 (0.008) |
