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J Clin Pathol 2000;53:803 doi:10.1136/jcp.53.10.803

Angiomyofibroblastoma of the vagina

  1. W G McCluggage1,
  2. R G White2
  1. 1Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast BT12 6BL, Northern Ireland
  2. 2Department of Obstetrics and Gynaecology, Mater Infirmorum Hospital Trust, Belfast BT14 6AB, Northern Ireland

      Angiomyofibroblastoma is a rare, recently described, soft tissue tumour that occurs mainly, but not exclusively, in the vulval region of premenopausal women.1 We report a case arising in the vagina to draw the attention of pathologists to the fact that this rare neoplasm can occur outside the vulva.

      A 54 year old woman, para 4 + 0, presented with a two year history of vaginal wall prolapse. Vaginal examination revealed a polypoid lesion on the anterior wall. Surgical removal and vaginal wall repair was performed.J Clin Pathol 2000;53:803–806

      The surgical specimen consisted of surface mucosa with an underlying well circumscribed, firm, homogenous, white coloured lesion measuring 2.5 cm in maximum diameter. Histology showed unremarkable surface squamous epithelium. Deep to this, a well circumscribed but unencapsulated lesion was present. This contained numerous randomly distributed blood …

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