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J Clin Pathol 53:791-793 doi:10.1136/jcp.53.10.791

An investigation of the Peutz-Jeghers gene (LKB1) in sporadic breast and colon cancers

Table 1

Allele loss and mutation rates for different populations

Population Carcinoma Number LOH Marker Mutations Ref
LOH, loss of heterozygosity, given as allele loss/number informative.
UK Breast 62 3/40 D19S565 Nil 12
Norwegian Colorectal 75 13/50 D19S886 Nil 15
Italian Colorectal 71 10/52 D19S886 1 16
Korean Colorectal 23 9/17 D19S886 5 13
6/15 D19S883 4
6/22 D19S565 3
UK Breast 30 1/15 D19S565 Nil Current
4/19 D19S886
Colorectal 23 2/13 D19S565 Nil
4/11 D19S886

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