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J Clin Pathol 2000;53:750-755 doi:10.1136/jcp.53.10.750

Whipple's disease revisited

  1. S A Misbah1,
  2. N P Mapstone1
  1. 1Yorkshire Regional Immunology Service and Molecular Pathology, The Leeds Teaching Hospitals Trust, Leeds General Infirmary, Leeds LS1 3EX, UK
  1. Dr Misbah sirajm{at}pathology.leeds.ac.uk
  • Accepted 28 April 2000

Abstract

Whipple's disease has traditionally been considered to be a rare multisystem disorder dominated by malabsorption. The recent identification of the Whipple's disease bacillus has, using polymerase chain reaction based assays, fuelled advances in the investigation, diagnosis, and management of this disease. This leader reviews the aetiology, clinical manifestations, investigation, and treatment of Whipple's disease in the light of this new information.

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