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J Clin Pathol 53:727-732 doi:10.1136/jcp.53.10.727

Modern laboratory diagnosis of mycobacterial infections

Table 3

Decision to treat analysis based on the availability of AFB smear and DAT result

High clinical suspicion of tuberculosis Low clinical suspicion of tuberculosis
Smear positive Smear negative Smear positive Smear negative
Action DAT result Action without DAT result Action with DAT result Action without DAT result Action with DAT result Action without DAT result Action with DAT result Action without DAT result Action with DAT result
This table is modified from Catanzaro et al.43
Question marks indicate that the clinical, public health, and laboratory groups could not agree on action in these cases, but instead recommend re-assessment of clinical details and repeat testing.
AFB, acid fast bacilli; DAT, direct amplification test.
Treat + Yes Yes Yes Yes Yes Yes No ?
Treat Yes ? Yes ? Yes No No No

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