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J Clin Pathol 15:497-500 doi:10.1136/jcp.15.6.497
  • Articles

Blood clotting factors in cerebrospinal fluid

  1. Stefan Niewiarowski1,
  2. Irena Hausmanowa-Petrusewicz,
  3. Zenon Wegrzynowicz2
  1. Department nof Neurology, the Medical School, Warsaw, Poland

      Abstract

      The activity of blood clotting factors has been investigated in cerebrospinal fluid. No cephalin-like activity was found in cerebrospinal fluid but prothrombin activity averaged about 0·5% of normal plasma activity. The activity of factor VII was negligible in almost all cases. The activity of antihaemophilic factors showed great variation but in the majority of cases it did not exceed 1% of normal plasma activity. High activity for factor V was found in almost all samples of cerebrospinal fluid.

      Footnotes

      • 1 Present address: Department of Physiological Chemistry, Medical School, Bialystok, Poland.

      • 2 Present address: Department of Health Protection, Institute of Nuclear Research, Warsaw-Zeran, Poland.