© 2000 Journal of Clinical Pathology
Leader
Neuropathology
1 Department of Neuropathology, Floor E, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
Correspondence to:
Dr Timperley
Footnotes
* CJD Surveillance Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK. Telephone (clinical office): 0131 332 2117; telephone (pathology office): 0131 537 1980; internet homepage: www.cjd.ed.ac.uk 
Accepted November 29, 1999
Health and safety
It is essential that staff are aware of the health and safety issues.1–16
The main danger of infection in neuropathology arises from the handling and processing of tissues from cases of AIDS, Creutzfeldt-Jakob disease (CJD), and tuberculosis.
All members of the department and mortuary staff should be immunised against hepatitis B. Because potentially dangerous cases can be encountered unexpectedly, technique should always be of a high standard and appropriate to the safety of all staff involved in the investigation. Any case of rapidly progressive dementia must be assumed to be a case of CJD until proved otherwise. The treatment of workplace, clothing, and instruments should be appropriate.
If a diagnosis of CJD is possible, samples of frozen brain, usually frontal lobe and cerebellum,
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