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Figure 9 High-grade dysplasia in Barrett’s oesophagus with a focal area highly suggestive of intramucosal adenocarcinoma. In the centre of the field is a proliferation of small glands in a back-to-back configuration, with little intervening lamina propria, which is difficult to explain on the basis of involvement of pre-existing crypts. There is a suggestion of isolated single cells in the lamina propria as well.
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