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Unusual mesenteric fibromuscular dysplasia– a rare cause for chronic intestinal ischaemia

Department of Pathology, Seth G S Medical College, Mumbai, India

Correspondence to:
Dr Pradeep Vaideeswar, Department of Pathology, Seth G S Medical College, Parel, Mumbai 400 012, India; shreeprajai@yahoo.co.in

Accepted 24 May 2007

Keywords: intestinal ischaemia; intestinal gangrene; artery; fibromuscular dysplasia

The first 150 words of the full text of this article appear below.

Fibromuscular dysplasia (FMD) was a term introduced by McCormack et al¹ to describe a rare non-atherosclerotic, non-inflammatory segmental occlusive disorder of medium-sized vessel arteries.² The FMD may be intimal, medial or periarterial, depending on the site of fibro-muscular proliferation.² Mesenteric arteries are uncommonly affected. Herein, we report an unusual petal-like FMD of mesenteric arteries produced by adventitial and periadventitial smooth muscle proliferation with an additional venous involvement.

	CASE HISTORY

 
An elderly patient, a non-smoker, presented with a 4-day history of abdominal pain, distension and constipation. Anti-tuberculous therapy had been instituted for 6 months for similar complaints 5 years ago. With a diagnosis of intestinal obstruction, an exploratory laparotomy was performed. A right hemi-colectomy was carried out. The specimen measured 33 cm. The resected ileum was dilated with mucosal and serosal congestion. Histologically, there was focal ulceration of the epithelium, along with submucosal oedema, vascular congestion and fibrosis. In . . . [Full text of this article]