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Recurrent cellular angiofibroma of the vulva

¹ Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast BT12 6BL, Northern Ireland, UK; glenn.mccluggage@bll.n-i.nhs.uk
² Department of Pathology, Belfast City Hospital Trust
³ Department of Surgery, Royal Group of Hospitals Trust

Keywords: vulva; cellular angiofibroma; immunohistochemistry; electron microscopy

Cellular angiofibroma is a benign mesenchymal lesion that was first described in 1997,¹ and which chiefly involves the vulval region. The original report described four cases of this distinctive lesion, all occurring in middle aged women, and the authors considered this to represent a benign neoplasm with little or no potential for local recurrence if excised with a rim of uninvolved normal tissue. Since then, an identical lesion has been described in a woman involving the subcutaneous tissue of the chest wall.² Similar lesions have also been reported in the inguinoscrotal region of men.^1,3 Here, we describe a vulval cellular angiofibroma that, although initially excised with a rim of normal tissue, exhibited tumour recurrence in a relatively short time period.

A 49 year old woman presented with a mass in the posterior aspect of the left labia majora. A well circumscribed lesion measuring 4 cm in diameter was excised with . . . [Full text of this article]